Which Test Should I Order for an Inpatient Evaluation of Cardiac Ischemia?

Rahul Aggarwal1, Deepak L Bhatt2

  • 1Brigham and Women's Hospital Heart and Vascular Center, Harvard Medical School, Boston.

NEJM Evidence
|June 25, 2024
PubMed

Insights

Choosing the right cardiac test for hospitalized patients with suspected ischemia is crucial. This review guides selecting appropriate stress or anatomical testing based on accurate risk stratification for obstructive coronary artery disease.

Area of Science:

  • Cardiology
  • Diagnostic Imaging
  • Internal Medicine

Background:

  • Cardiac ischemia and obstructive coronary artery disease (CAD) are common in hospitalized patients.
  • Numerous diagnostic testing options are available, complicating clinical decision-making.
  • Accurate risk stratification is essential for selecting the most appropriate cardiac test.

Purpose of the Study:

  • To provide a guide for selecting appropriate cardiac ischemia testing in the inpatient setting.
  • To differentiate between stress (functional) and anatomical testing modalities.
  • To illustrate test selection considerations using clinical case examples.

Main Methods:

  • Review of current diagnostic testing strategies for cardiac ischemia.
  • Categorization of tests into stress testing (functional) and anatomical testing.
  • Application of risk stratification principles to test selection.

Main Results:

  • Stress testing evaluates for ischemia, with or without imaging.
  • Anatomical testing visualizes obstructive CAD.
  • Test selection depends on patient-specific factors and risk assessment.

Conclusions:

  • Choosing the optimal test for inpatient cardiac ischemia evaluation requires careful consideration of available options.
  • Understanding the distinct roles of stress and anatomical testing is key.
  • Risk stratification guides the selection of the most informative diagnostic test.

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