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Updated: Jun 23, 2025

Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine
Published on: June 13, 2022
New insides into chimeric and hybrid azines derivatives with antifungal activity
Tiberius Balaes1, Camelia Georgiana Marandis2, Violeta Mangalagiu3,4
1Alexandru Ioan Cuza University of Iasi, Department of Biology, Faculty of Biology, 20A Carol 1st Bvd, Iasi, 700505, Romania.
Abstract:
During the last decades, five or six member rings azaheterocycles compounds appear to be an extremely valuable source of antifungal agents. Their use seems to be a very attractive solution in antifungal therapy and to overcome antifungal resistance in agriculture. The present review highlights the main results obtained in the field of hybrid and chimeric azine (especially pyridine, quinoline, phenanthroline, bypyridine, naphthyridine and their fused derivatives) derivatives presented in scientific literature from the last 10 years, with emphasis on antifungal activity of the mentioned compounds. A special attention was played to hybrid and chimeric azole-azine class, having in view the high antifungal potential of azoles.
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