Prevalent morphometric vertebral fractures as a risk factor for subsequent clinical vertebral fractures after shortfusion surgery in older Japanese women with degenerative spondylolisthesis
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View abstract on PubMed
Summary
This summary is machine-generated.Prevalent vertebral fractures (VFs) increase the risk of subsequent clinical VFs after short-fusion surgery in older women with degenerative spondylolisthesis. This finding highlights the importance of assessing prior VFs in surgical planning.
Area Of Science
- Orthopedics
- Geriatric Medicine
- Radiology
Background
- Vertebral fractures (VFs) are common in osteoporosis, impacting quality of life.
- Subsequent VFs are a known complication following instrumented fusion for degenerative lumbar disorders.
- Previous studies suggest prevalent VFs increase subsequent VF incidence in postmenopausal women, but data specific to fusion surgery is limited.
Purpose Of The Study
- To determine if prevalent morphometric vertebral fractures (VFs) are a risk factor for subsequent clinical VFs.
- To investigate this risk in women aged 60 years and older undergoing short-fusion surgery for degenerative spondylolisthesis.
Main Methods
- A retrospective cohort study included 237 older female patients, categorized by the presence (VF [+]) or absence (VF [-]) of prevalent morphometric VFs.
- The Kaplan-Meier method was used to compare the time to subsequent clinical VFs after fusion surgery between groups.
- Propensity-score matching was applied to adjust for potential confounders, analyzing 40 VF (+) patients and 80 VF (-) patients.
Main Results
- The VF (+) group exhibited a higher incidence of subsequent clinical VFs compared to the VF (-) group.
- Prevalent morphometric VFs were identified as an independent risk factor for subsequent clinical VFs prior to matching.
- Kaplan-Meier analysis confirmed these findings post-propensity-score matching.
Conclusions
- Prevalent morphometric vertebral fractures are a potential risk factor for subsequent clinical VFs.
- This risk is particularly relevant for older women with degenerative spondylolisthesis who have undergone short-fusion surgery.
- Preoperative assessment of vertebral fractures may be crucial for surgical decision-making and patient management.
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