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Updated: Jun 23, 2025

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
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A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators

Published on: February 20, 2018

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Multiple recent HCAR2 structures demonstrate a highly dynamic ligand binding and G protein activation mode

Aslihan Shenol1, Ricardo Tenente1, Michael Lückmann1

  • 1Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Nature Communications
|June 25, 2024
PubMed

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