Downregulated CDK10 promotes cancer progression and radioresistance in lung cancer through activating the JNK/c-Jun signaling pathway
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View abstract on PubMed
Summary
This summary is machine-generated.Cyclin-dependent kinase 10 (CDK10) is downregulated in lung cancer, promoting cell growth and radioresistance by activating the JNK/c-Jun pathway. Restoring CDK10 may offer a new therapeutic strategy for lung cancer.
Area Of Science
- Oncology
- Molecular Biology
- Cell Biology
Background
- Lung cancer presents significant morbidity and mortality.
- Cyclin-dependent kinase 10 (CDK10) is implicated in cancer progression and metastasis.
- The specific role of CDK10 in lung cancer radioresistance requires further investigation.
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