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Updated: Jun 23, 2025
LAD-Ligation: A Murine Model of Myocardial Infarction
Published on: October 14, 2009
Stepping into the Light: Defining Culprit Lesion in Non-ST Elevation Myocardial Infarction
Aditya D Pradana1, Arditya Damarkusuma1, Hariadi Hariawan1
1Department of Cardiology and Vascular Medicine, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada - Dr. Sardjito General Hospital, Yogyakarta, Indonesia.
Insights
Identifying the infarct-related artery in non-ST-segment-elevation myocardial infarction (NSTEMI) is difficult. This case report highlights how ventricular tachycardia morphology and ECG clues aided successful percutaneous coronary intervention in the left circumflex artery.
Area of Science:
- Cardiology
- Interventional Cardiology
Background:
- Identifying the infarct-related artery (IRA) in non-ST-segment-elevation acute myocardial infarction (NSTEMI) is clinically challenging.
- Multivessel coronary artery disease (CAD), diffuse disease, or non-significant CAD often complicates IRA identification via angiography.
- Limitations in performing intracoronary imaging further exacerbate this diagnostic challenge in certain healthcare settings.
Abstract:
Identifying the infarct-related artery (IRA) in a non-ST-segment-elevation acute myocardial infarction (NSTEMI) can be very challenging, particularly in a hospital that cannot perform intracoronary imaging due to certain limitations. This is because, by angiography, most patients present with multivessel coronary artery disease (CAD), diffuse disease, or non-significant CAD. We present a case of a 60-year-old female patient presented with substernal chest pain and palpitations of 6 h duration. The first hospital contact 12-lead electrocardiogram (ECG) showed ventricular tachycardia (VT) with unstable hemodynamics, after stabilization patient was transported to the catheterization laboratory for immediate percutaneous coronary intervention (PCI). With a clue of VT morphology, post-converted ECG, and coronary angiography, the patient successfully underwent PCI in the left circumflex artery.
