Pediatric Surgical Opioid Prescribing by Procedure, 2020-2021

Kao-Ping Chua1, Chad M Brummett2,3, Lorraine I Kelley-Quon4,5

  • 1Susan B. Meister Child Health Evaluation and Research Center, and Departments of Pediatrics.

Pediatrics
|June 26, 2024
PubMed

Insights

Pediatric surgical opioid prescribing is concentrated in a few procedures, notably tonsillectomy and adenoidectomy. Targeting these common surgeries can reduce overall opioid use in children and adolescents.

Area of Science:

  • Pediatric Surgery
  • Pain Management
  • Opioid Stewardship

Background:

  • Surgery is a primary reason for prescribing opioids to pediatric patients.
  • Understanding which surgical procedures drive opioid prescribing is crucial for targeted interventions.

Purpose of the Study:

  • To identify specific surgical procedures associated with the highest pediatric opioid prescribing.
  • To analyze opioid prescribing patterns in different age groups within the pediatric population.

Main Methods:

  • Cross-sectional analysis of commercial and Medicaid claims (2020-2021).
  • Included surgical procedures for patients aged 0-21 years.
  • Calculated total opioid prescriptions in morphine milligram equivalents (MMEs) within 3 days of discharge.

Main Results:

  • For younger children (0-11 years), tonsillectomy/adenoidectomy accounted for 50.3% of post-surgical MMEs.
  • In adolescents (12-21 years), tonsillectomy/adenoidectomy (12.7%), knee arthroscopy (12.6%), and cesarean delivery (7.8%) were top procedures.
  • Top 3 procedures accounted for over 59% of MMEs in younger children and 33% in adolescents.

Conclusions:

  • Pediatric surgical opioid prescribing is highly concentrated among a limited number of procedures.
  • Opioid stewardship initiatives focused on these high-prescribing procedures can effectively reduce pediatric opioid exposure.
  • This targeted approach aims to minimize opioid risks while ensuring adequate pain management post-surgery.
Abstract

Related Concept Videos

Opioid Analgesics: Synthetic and Semisynthetic Opioids01:15

Opioid Analgesics: Synthetic and Semisynthetic Opioids

Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
273
Parenteral Anesthetics: Overview01:24

Parenteral Anesthetics: Overview

Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
117
Prescription, Nonprescription and Orphan Drugs01:02

Prescription, Nonprescription and Orphan Drugs

Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
717
Opioid Analgesics: Morphine and Other Natural Cogeners01:20

Opioid Analgesics: Morphine and Other Natural Cogeners

Opioids are a class of drugs that mimic endogenous opioid peptides and act on opioid receptors, and help in pain relief. These compounds are classified as natural, synthetic, or semi-synthetic. Natural opioids, like morphine, codeine, and thebaine, are derived from the opium poppy plant (Papaver somniferum or Papaver album) and are termed opiates. Synthetic opioids are artificial, while semi-synthetic opioids combine natural and synthetic compounds. Morphine, a prototypical opioid, possesses a...
229
Local Anesthetics: Clinical Application as Epidural Anesthesia01:29

Local Anesthetics: Clinical Application as Epidural Anesthesia

Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
428
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
71