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Published on: June 4, 2012
The Application of Rat Models in Staphylococcus aureus Infections
Hongyue Liang1, Yadong Wang2, Fang Liu1
1Department of Epidemiology, School of Public Health, Zhengzhou University, Zhengzhou 450001, China.
Abstract:
Staphylococcus aureus (S. aureus) is a major human pathogen and can cause a wide range of diseases, including pneumonia, osteomyelitis, skin and soft tissue infections (SSTIs), endocarditis, mastitis, bacteremia, and so forth. Rats have been widely used in the field of infectious diseases due to their unique advantages, and the models of S. aureus infections have played a pivotal role in elucidating their pathogenic mechanisms and the effectiveness of therapeutic agents. This review outlined the current application of rat models in S. aureus infections and future prospects for rat models in infectious diseases caused by S. aureus.
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