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Muscle resection biopsy during peroral endoscopic myotomy in a patient with achalasia

Shinya Hoki1, Hirofumi Abe1, Chise Ueda1

  • 1Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Hyogo, Japan.

Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society
|June 26, 2024
PubMed
Abstract

No abstract available in PubMed .

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Esophageal Achalasia01:27

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Esophageal achalasia is a chronic neurogenic disorder characterized by impaired relaxation of the lower esophageal sphincter (LES) and absent or ineffective peristalsis in the distal esophagus. This leads to a functional obstruction without a physical blockage, despite significant disruption of esophageal motility.EtiologyAchalasia is caused by degeneration of the myenteric (Auerbach's) plexus, specifically the loss of inhibitory ganglion cells that produce vasoactive intestinal peptide (VIP)...