Onychomatricomas: Assessing Surgical Outcomes

Area of Science:

• Dermatology
• Oncology
• Surgical Pathology

Background:

• Onychomatricoma (OM) is a rare benign nail matrix tumor.
• Surgical treatment is standard, but limited data exist on outcomes.

Purpose of the Study:

• Review surgical cases of OM.
• Assess the relationship between lesion characteristics (location, thickness, width) and postoperative outcomes.

Main Methods:

• Retrospective review of 62 patient records (1998-2023).
• Analysis of 41 eligible patients' surgical outcomes.
• Comparison of tangential excision versus lateral longitudinal excision.

Main Results:

• 71% of patients undergoing tangential excision achieved normal nail regrowth.
• Tumors >3 mm thick and involving total nail width had a 60% sequelae rate.
• Lesion location (medial/lateral) did not influence outcomes.

Conclusions:

• Tangential excision is effective for OM, yielding normal regrowth in most cases.
• Tumor thickness and width are critical factors predicting postoperative sequelae.
• Nail plate location is not a significant prognostic factor for OM treatment outcomes.