Stereoselective activation of vicinal dihalogen compounds to mutagens by glutathione conjugation

Site specific rectal drug administration in man with an osmotic system: influence on "first-pass" elimination of lidocaine.

Pharmaceutical research·2013

Avoidance of "first-pass" elimination of rectally administered propranolol in relation to the site of absorption in rats.

Pharmaceutical research·2013

Correlation between in vivo antipyrine metabolite formation and theophylline metabolism in rats.

Pharmaceutical research·2013

Carcinogenic activity of benzo[a]pyrene in a 2 year oral study in Wistar rats.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association·2011

P-glycoprotein inhibition leads to enhanced disruptive effects by anti-microtubule cytostatics at the in vitro blood-brain barrier.

Pharmaceutical research·2001

Active efflux of the 5-HT(1A) receptor agonist flesinoxan via P-glycoprotein at the blood-brain barrier.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences·2001

Marine-derived ophiobolin MHO7 targets voltage-dependent anion channel 2 and promotes its degradation in triple-negative breast cancer.

Biochemical pharmacology·2026

ECDD-S16 exhibits broad-spectrum antiviral activity and inhibits an early, pH-dependent step of influenza virus entry.

Biochemical pharmacology·2026

Repurposing the gastroprotective agent geranylgeranylacetone for atherosclerosis: a novel role of the HSP22-Nrf2-mitochondrial axis.

Biochemical pharmacology·2026

Chemical proteomics and phenotypic profiling identify αFOD as a podophyllotoxin-derived PGK1 inhibitor that suppresses glycolysis and proliferation in hepatocellular carcinoma.

Biochemical pharmacology·2026

Non-histone protein lactylation in cancer metastasis: From metabolic reprogramming to therapeutic targeting.

Biochemical pharmacology·2026

Nucleoside antitumor drugs: From molecular mechanisms and adaptive resistance to clinical translation.

Biochemical pharmacology·2026

Erratum: [Corrigendum] Ginsenoside Rg1 ameliorates apoptosis, senescence and oxidative stress in ox-LDL-induced vascular endothelial cells via the AMPK/SIRT3/p53 signaling pathway.

Experimental and therapeutic medicine·2026

Hydrogen sulfide-mediated vasodilation requires heme oxygenase-derived carbon monoxide.

bioRxiv : the preprint server for biology·2026

Photometallobiocatalytic Asymmetric Radical-Mediated Cross-Coupling of Organotrifluoroborate Salts and Pyridotriazoles.

bioRxiv : the preprint server for biology·2026

Mitochondrial Signaling: Nitric Oxide Synthesis by Cytochrome c Oxidase and Its Oxygen Sensitivity Are Modulated by Adenine Nucleotides.

bioRxiv : the preprint server for biology·2026

Carbonyl-Site-Mediated Oxygen Reduction in Fluorenone-Based Covalent Organic Frameworks for Efficient Hydrogen Peroxide Photosynthesis.

Advanced materials (Deerfield Beach, Fla.)·2026

Photoinduced metal-free cascade silylation/cyclization of alkynes/alkynones with hydrosilanes to access 3-silylated benzothiophenes and thioflavones.

Organic & biomolecular chemistry·2026

Related Experiment Videos

Stereoselective activation of vicinal dihalogen compounds to mutagens by glutathione conjugation

Related Concept Videos

Site specific rectal drug administration in man with an osmotic system: influence on "first-pass" elimination of lidocaine.

Avoidance of "first-pass" elimination of rectally administered propranolol in relation to the site of absorption in rats.

Correlation between in vivo antipyrine metabolite formation and theophylline metabolism in rats.

Carcinogenic activity of benzo[a]pyrene in a 2 year oral study in Wistar rats.

P-glycoprotein inhibition leads to enhanced disruptive effects by anti-microtubule cytostatics at the in vitro blood-brain barrier.

Active efflux of the 5-HT(1A) receptor agonist flesinoxan via P-glycoprotein at the blood-brain barrier.

Marine-derived ophiobolin MHO7 targets voltage-dependent anion channel 2 and promotes its degradation in triple-negative breast cancer.

ECDD-S16 exhibits broad-spectrum antiviral activity and inhibits an early, pH-dependent step of influenza virus entry.

Repurposing the gastroprotective agent geranylgeranylacetone for atherosclerosis: a novel role of the HSP22-Nrf2-mitochondrial axis.

Chemical proteomics and phenotypic profiling identify αFOD as a podophyllotoxin-derived PGK1 inhibitor that suppresses glycolysis and proliferation in hepatocellular carcinoma.

Non-histone protein lactylation in cancer metastasis: From metabolic reprogramming to therapeutic targeting.

Nucleoside antitumor drugs: From molecular mechanisms and adaptive resistance to clinical translation.

Erratum: [Corrigendum] Ginsenoside Rg1 ameliorates apoptosis, senescence and oxidative stress in ox-LDL-induced vascular endothelial cells via the AMPK/SIRT3/p53 signaling pathway.

Hydrogen sulfide-mediated vasodilation requires heme oxygenase-derived carbon monoxide.

Photometallobiocatalytic Asymmetric Radical-Mediated Cross-Coupling of Organotrifluoroborate Salts and Pyridotriazoles.

Mitochondrial Signaling: Nitric Oxide Synthesis by Cytochrome c Oxidase and Its Oxygen Sensitivity Are Modulated by Adenine Nucleotides.

Carbonyl-Site-Mediated Oxygen Reduction in Fluorenone-Based Covalent Organic Frameworks for Efficient Hydrogen Peroxide Photosynthesis.

Photoinduced metal-free cascade silylation/cyclization of alkynes/alkynones with hydrosilanes to access 3-silylated benzothiophenes and thioflavones.

Related Experiment Videos

Stereoselective activation of vicinal dihalogen compounds to mutagens by glutathione conjugation

Related Concept Videos

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