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Induction of Drug-Induced, Autoimmune Hepatitis in BALB/c Mice for the Study of Its Pathogenic Mechanisms
Published on: May 29, 2020
Autoimmune hepatitis in teenage pregnancy with good obstetric outcome
Sonia Arnowalt1, Lynda Verghese2
1Obstetrics and Gynaecology, Wrexham Maelor Hospital, Betsi Cadwaladr University Health Board, North Wales, UK sonueby@gmail.com.
Abstract:
Autoimmune hepatitis (AIH) is a rare liver disorder having long-standing inflammatory features. It classically affects women of reproductive age and can have adverse maternal and fetal outcomes during the pregnancy. The course of the disease is unpredictable and there have been flares even in stable patients. There are limited reports of its management in pregnancy. Furthermore, clinicians may encounter more pregnancies complicated by AIH due to advances in the treatment of AIH. We report a case of unplanned pregnancy in a young teenager who had been diagnosed with AIH. This case report summarises the risks, investigations, treatment and prevention of complications to achieve a favourable outcome in pregnancy. We highlight the importance of tight surveillance by a multidisciplinary team involving maternal medicine specialists and hepatology teams to achieve a good obstetric outcome in a district hospital like ours.
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