Flecainide overdose-induced wide-complex tachyarrhythmia treated with sodium bicarbonate infusion
James Boris1, Hussein Al-Sudani2, Aaron Brophy2
1Internal Medicine, Albert Einstein Medical Center Montgomery, East Norriton, PA, USA james.boris@jefferson.edu.
Abstract:
Flecainide is a medication used to treat supraventricular and ventricular tachyarrhythmias. Cases of overdoses are rare, however, can lead to significant cardiac effects. In previous cases of flecainide toxicity, treatment with sodium bicarbonate, intravenous lipid emulsion and amiodarone have been reported to be effective in preventing cardiovascular collapse and reestablishing baseline rhythm. Here, we present a case of a man in his 40s presented with flecainide overdose with wide-complex tachycardia that was treated with intravenous sodium bicarbonate following failure of amiodarone to normalise QRS interval.
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