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TNIP3 protects against pathological cardiac hypertrophy by stabilizing STAT1

Hongjie Shi1,2, Yongjie Yu1,2, Dajun Li1,2

  • 1Taikang Medical School (School of Basic Medical Sciences), Wuhan University, 430000, Wuhan, China.

Cell Death & Disease
|June 26, 2024
PubMed
Summary

TNFAIP3 interacting protein 3 (TNIP3) suppresses pathological cardiac hypertrophy by stabilizing STAT1. This discovery offers a new therapeutic target for heart failure and related cardiovascular diseases.

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