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Published on: August 11, 2015
A 5-Year Follow-Up after Endovascular Treatment of 402 Intracranial Aneurysms-A Single-Centre Experience
Ana Repić Buličić1, David Ozretić2, Marko Radoš2
1Department of Neurology, University Hospital Split, 21000 Split, Croatia.
Insights
Endovascular treatment for intracranial aneurysms, both ruptured and unruptured, demonstrates favorable outcomes and safety. This study highlights effective long-term results with acceptable complication rates for coiling and stenting procedures.
Area of Science:
- Neurosurgery
- Interventional Neuroradiology
- Vascular Neurology
Background:
- Intracranial aneurysms pose significant risks, necessitating effective treatment strategies.
- Endovascular techniques offer minimally invasive options for managing ruptured and unruptured aneurysms.
- Evaluating long-term outcomes is crucial for understanding the durability and safety of endovascular repair.
Purpose of the Study:
- To assess early and long-term clinical and morphological outcomes of endovascular treatment for intracranial aneurysms.
- To compare outcomes between ruptured aneurysms (RAs) and unruptured aneurysms (UAs).
- To evaluate the safety and efficacy of endovascular methods (coils, stents) in a single-center cohort.
Main Methods:
- Retrospective analysis of 402 endovascularly treated intracranial aneurysms (coils, stents, or both).
- Average follow-up duration of 5.5 years.
- Analysis of patient demographics, risk factors, aneurysm characteristics, and clinical/angiographic outcomes, comparing RAs and UAs.
Main Results:
- Good early clinical outcomes achieved in 78.5% of RAs and 95.3% of UAs.
- Complication rates: 19.55% for UAs and 19.55% for RAs. Periprocedural rupture rates: 0.8% (UAs) and 2.2% (RAs). Thromboembolic events: 4.8% (UAs) and 8% (RAs).
- Retreatment due to recanalization required in 9.21% of UAs and 16.66% of RAs.
Conclusions:
- Endovascular treatment provides favorable clinical outcomes for both ruptured and unruptured intracranial aneurysms.
- The procedures demonstrate acceptable periprocedural complication rates.
- Endovascular methods are proven safe and effective for managing intracranial aneurysms.
Abstract:
The aim of our study was to evaluate the early and long-term clinical and morphological outcomes of the endovascular treatment of ruptured and non-ruptured intracranial aneurysms in a cohort of patients from a single centre. We retrospectively analysed the treatment outcomes of 402 endovascularly treated intracranial aneurysms with an average follow-up of 5.5 years. All included patients were treated with endovascular techniques (coil, stent or both). We analysed patient demographics, risk factors for an aneurysm rupture, aneurysm characteristics, and clinical and angiographic complications and outcomes. We analysed and compared the data from the two groups, ruptured aneurysms (RAs) and unruptured aneurysms (UAs), separately. Out of the 318 patients included, a good early clinical outcome was achieved in 78.5% of RAs and in 95.3% of UAs. No complications occurred in 87.71% of patients with UAs and in 80.45% with RAs. The periprocedural rupture rate for UAs and RAs was 0.8% and 2.2%, respectively. The rate of thromboembolic events was 4.8 and 8% for UAs and RAs, respectively. A retreatment due to the recanalisation was required in 9.21% of patients with UAs and in 16.66% of patients with RAs. The results from our centre showed an overall favourable clinical outcome with acceptable periprocedural complications for both RAs and UR aneurysms and proved the endovascular method as safe and effective in the treatment of intracranial aneurysms.
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