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Related Concept Videos

Cancer Therapies02:49

Cancer Therapies

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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
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Revolutionizing Brain Tumor Care: Emerging Technologies and Strategies.

Trang T T Nguyen1, Lloyd A Greene2, Hayk Mnatsakanyan3

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Glioblastoma multiforme (GBM) is an aggressive brain tumor with poor prognosis. This review highlights advanced treatments and technologies to overcome drug delivery challenges and improve outcomes for brain tumor patients.

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TTFieldsartificial intelligence (AI)external beam radiation therapyfMRIgene and cell therapyglioblastoma multiformeimmunotherapytargeted therapytemozolomide

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Area of Science:

  • Neuro-oncology
  • Drug Delivery Systems
  • Biomedical Engineering

Background:

  • Glioblastoma multiforme (GBM) is a highly aggressive brain tumor with a median survival of 12-16 months.
  • Current treatments (surgery, radiation, chemotherapy) have limited efficacy due to the blood-brain barrier and therapeutic resistance.
  • Tumor recurrence is common, necessitating novel therapeutic strategies.

Purpose of the Study:

  • To review cutting-edge technologies for brain tumor treatment.
  • To highlight advanced therapies in development for glioblastoma.
  • To provide insights for patients on emerging brain tumor treatment options.

Main Methods:

  • Literature review of current and emerging brain tumor therapies.
  • Focus on technologies addressing drug delivery and therapeutic resistance.
  • Analysis of advancements in glioblastoma treatment strategies.

Main Results:

  • Significant challenges exist in delivering therapeutics across the blood-brain barrier.
  • Therapeutic resistance remains a major hurdle in glioblastoma treatment.
  • Emerging technologies show promise in overcoming current treatment limitations.

Conclusions:

  • Advanced treatment modalities are crucial for improving glioblastoma outcomes.
  • Overcoming drug delivery and resistance barriers is key to reducing tumor recurrence.
  • Ongoing research offers hope for more effective brain tumor therapies.