Exploring Predictive Factors for Heart Failure Progression in Hypertensive Patients Based on Medical Diagnosis Data...

Area of Science:

• Cardiology
• Medical Informatics
• Public Health

Background:

• Heart failure significantly increases mortality, particularly in hypertensive patients.
• Early identification of heart failure progression factors in hypertension is critical for timely intervention.
• Utilizing pre-hypertension diagnostic history aids in predicting heart failure onset at hypertension diagnosis.

Purpose of the Study:

• To identify predictive factors for heart failure progression in hypertensive individuals.
• To analyze age-specific predictive factors using distinct age groups.
• To provide insights for improved risk assessment in hypertensive patients.

Main Methods:

• Utilized the MIMIC-IV database for hypertension patient medical diagnosis records.
• Employed chi-square tests and XGBoost modeling for factor identification.
• Analyzed age-specific predictive factors across four groups: all ages, 0-65, 65-80, and over 80 years.

Main Results:

• Chi-square tests identified varying numbers of factors per age group (34 for all ages, decreasing with age).
• XGBoost modeling revealed an increasing number of factors with age (19 for all ages, up to 33 for over 80).
• Overall, 21 predictive factors were identified, including atrial fibrillation, anticoagulant use, kidney failure, obstructive pulmonary disease, and anemia.

Conclusions:

• The study identified key predictors for heart failure in hypertensive patients.
• Findings highlight the importance of considering specific comorbidities and treatments in risk assessment.
• The identified factors can inform clinical practice for proactive heart failure management in hypertension.