The Biomedical Applications of Biomolecule Integrated Biosensors for Cell Monitoring

Area of Science:

• Biomedical Engineering
• Analytical Chemistry
• Cell Biology

Background:

• Cell monitoring is crucial for understanding physiological states and abnormalities caused by various stimuli.
• Traditional instrument-based analysis is being superseded by advanced sensor systems for cell analysis.
• Sensor systems detect biological markers like surface proteins, membrane components, metabolites, and DNA.

Purpose of the Study:

• To review fundamental principles of sensor systems for cell monitoring.
• To focus on biosensing systems, including sensing and signal-transducing elements.
• To highlight recent advancements, applications, challenges, and future prospects of biosensors.

Main Methods:

• Review of existing literature on chemical sensors and biosensors for cell monitoring.
• Classification of sensor systems based on target recognition components.
• Analysis of sensing and signal-transducing elements in biosensing systems.

Main Results:

• Sensor systems offer enhanced methods for detecting cell abnormalities and metabolites.
• Biosensors and chemical sensors are key technologies in modern cell monitoring.
• Recent advancements show significant progress in biosensor applications.

Conclusions:

• Sensor systems, particularly biosensors, provide valuable insights into cell health and disease.
• Addressing current challenges is essential for enhancing biosensor performance.
• Further research in biosensing holds promise for biomedical applications.