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Updated: Jun 22, 2025

Tissue-specific miRNA Expression Profiling in Mouse Heart Sections Using In Situ Hybridization
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MicroRNA Expression in Patients with Coronary Artery Disease and Hypertension-A Systematic Review

Bartosz Kondracki1, Mateusz Kłoda1, Anna Jusiak-Kłoda1

  • 1Department of Cardiology, Medical University of Lublin, 20-059 Lublin, Poland.

International Journal of Molecular Sciences
|June 27, 2024
PubMed

Insights

MicroRNAs (miRNAs) show complex roles in coronary artery disease (CAD) and hypertension. Further research is needed to validate their potential as biomarkers and therapeutic targets for cardiovascular diseases.

Area of Science:

  • Cardiovascular Medicine
  • Molecular Biology
  • Genetics

Background:

  • Coronary artery disease (CAD) and hypertension are leading causes of cardiovascular morbidity and mortality.
  • MicroRNAs (miRNAs) are increasingly recognized for their roles in cardiovascular pathophysiology.
  • Identifying reliable biomarkers and therapeutic targets for these conditions is crucial.

Conclusions:

  • miRNAs represent promising, yet complex, biomarkers for CAD and hypertension.
  • Targeted interventions modulating miRNA activity hold potential for novel therapeutic strategies.
  • Further research is essential to validate findings and elucidate precise miRNA functions in cardiovascular disease progression.

Keywords:
MicroRNA expressioncoronary artery diseasehypertension

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