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Correlation between DWI-ASPECTS Score, Ischemic Stroke Volume on DWI, Clinical Severity and Short-Term Prognosis: A
Oana Andreea Dogariu1, Veronica Gheorman2, Ioan Dogariu3
1Ph.D. School Department, University of Medicine and Pharmacy of Craiova, Petru Rareș 2 Str., 200349 Craiova, Romania.
Brain Sciences
|June 27, 2024
Summary
Acute ischemic stroke severity, measured by NIHSS score, strongly correlates with stroke volume and short-term prognosis. Diffusion-weighted imaging (DWI) is crucial for assessing stroke severity and predicting outcomes.
Area of Science:
- Neurology
- Radiology
- Public Health
Background:
- Ischemic stroke is a growing public health concern, with incidence projected to double in individuals over 75.
- Optimizing patient management requires correlating clinical severity with ischemic stroke volume.
Purpose of the Study:
- To correlate clinical severity (NIHSS score) with ischemic stroke volume (DWI) and short-term prognosis (mRS score).
Main Methods:
- Study included 43 acute ischemic stroke patients from January to December 2023.
- Correlations assessed using Spearman and multiple linear regression analyses.
- NIHSS, ASPECTS-DWI, stroke volume, and mRS scores were evaluated.
Main Results:
- Strong positive correlation found between NIHSS score and ischemic stroke volume (r=0.982, p<0.01).
- Strong negative correlation observed between ASPECTS-DWI score and mRS score (r=-0.952, p<0.01).
- ASPECTS, stroke volume, and NIHSS collectively predicted outcomes (R²=0.94, p<0.001).
Conclusions:
- Diffusion-weighted imaging (DWI) is vital for assessing ischemic stroke severity.
- DWI aids in predicting short-term prognosis, supporting its clinical integration.
- Findings highlight DWI's role in acute ischemic stroke management.
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