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Updated: Jun 22, 2025

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Diagnostic Role of Multi-Detector Computed Tomography in Acute Mesenteric Ischemia
Francesco Michele Ronza1, Teresa Letizia Di Gennaro2, Gianfranco Buzzo1
1Department of Diagnostic Imaging, AORN "S. Anna e S. Sebastiano", 81100 Caserta, Italy.
Insights
Diagnosing acute mesenteric ischemia is difficult due to non-specific symptoms. Multi-Detector CT Angiography (MDCTA) is crucial for early detection, guiding treatment by identifying thrombosis and disease extent.
Area of Science:
- Radiology
- Gastroenterology
- Vascular Surgery
Background:
- Acute mesenteric ischemia (AMI) presents with non-specific symptoms, leading to delayed diagnosis and high mortality (up to 50%).
- Early diagnosis is critical for effective management, differentiating between conditions amenable to non-operative management (NOM) and those requiring surgery.
Purpose of the Study:
- To detail the optimal CT Angiography (CTA) protocol for diagnosing AMI.
- To elucidate the arterial and venous supply of the gastrointestinal tract and associated ischemic patterns on CTA.
- To describe key CT findings, including vascular, bowel, and extraintestinal signs, for accurate AMI diagnosis.
Main Methods:
- Review of optimal CT Angiography (CTA) protocols for acute mesenteric ischemia.
- Analysis of CTA imaging patterns of gastrointestinal arterial and venous supply.
- Correlation of CT findings with disease severity and management strategies.
Main Results:
- MDCTA is the primary imaging modality for suspected AMI, accurately detecting thrombosis and disease extent.
- CTA provides essential information to differentiate between non-operative management (NOM) and surgical intervention.
- Specific CT imaging patterns of vascular compromise, bowel wall changes, and extraintestinal findings aid prompt diagnosis.
Conclusions:
- MDCTA is indispensable for the timely and accurate diagnosis of acute mesenteric ischemia.
- Understanding CTA protocols and imaging patterns is vital for emergency settings.
- MDCTA facilitates appropriate clinical and surgical management decisions, potentially improving patient outcomes.
Abstract:
Mesenteric ischemia diagnosis is challenging, with an overall mortality of up to 50% of cases despite advances in treatment. The main problem that affects the outcome is delayed diagnosis because of non-specific clinical presentation. Multi-Detector CT Angiography (MDCTA) is the first-line investigation for the suspected diagnosis of vascular abdominal pathologies and the diagnostic test of choice in suspected mesenteric bowel ischemia. MDCTA can accurately detect the presence of arterial and venous thrombosis, determine the extent and the gastrointestinal tract involved, and provide detailed information determining the subtype and the stage progression of the diseases, helping clinicians and surgeons with appropriate management. CT (Computed Tomography) can differentiate forms that are still susceptible to pharmacological or interventional treatment (NOM = non-operative management) from advanced disease with transmural necrosis in which a surgical approach is required. Knowledge of CT imaging patterns and corresponding vascular pathways is mandatory in emergency settings to reach a prompt and accurate diagnosis. The aims of this paper are 1. to provide technical information about the optimal CTA (CT Angiography) protocol; 2. to explain the CTA arterial and venous supply to the gastrointestinal tract and the relevant ischemic pattern; and 3. to describe vascular, bowel, and extraintestinal CT findings for the diagnosis of acute mesenteric ischemia.
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