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Hemodynamic Precision in the Neonatal Intensive Care Unit using Targeted Neonatal Echocardiography
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Exploring Cardiovascular Involvement in Tuberous Sclerosis: Insights for Pediatric Clinicians

Cecilia Lazea1,2, Ioana Țaranu3, Sorana D Bolboacă3

  • 1Pediatric Clinic 1, Emergency Pediatric Hospital, Calea Moților, No. 68, 400370 Cluj-Napoca, Romania.

Children (Basel, Switzerland)
|June 27, 2024
PubMed

Insights

Tuberous sclerosis can affect children's hearts, causing cardiac rhabdomyomas and arrhythmias. Early pediatrician recognition and management of these cardiovascular issues improve quality of life.

Area of Science:

  • Pediatrics
  • Cardiology
  • Genetics

Background:

  • Tuberous sclerosis is a rare genetic disorder primarily affecting the nervous and cardiovascular systems.
  • Cardiovascular manifestations, including cardiac rhabdomyomas and arrhythmias, are common in children with tuberous sclerosis.
  • Early identification of cardiac issues is crucial for effective management and improved patient outcomes.

Purpose of the Study:

  • To equip pediatric practitioners with current knowledge on cardiovascular complications in children with tuberous sclerosis.
  • To review the evolution of cardiovascular manifestations from antenatal to postnatal stages.
  • To outline strategies for systematic screening and long-term follow-up of cardiac rhabdomyomas and arrhythmias.

Main Methods:

  • Literature review focusing on cardiovascular manifestations in tuberous sclerosis.
  • Overview of antenatal and postnatal cardiac feature evolution.
  • Discussion of screening and follow-up protocols for cardiac rhabdomyomas and arrhythmias.

Main Results:

  • Cardiac rhabdomyomas and arrhythmias are often the initial cardiac signs of tuberous sclerosis.
  • Clinical manifestations of cardiac rhabdomyomas can be diverse, posing diagnostic challenges.
  • Understanding the progression of cardiovascular issues aids in timely intervention.

Conclusions:

  • Pediatricians play a vital role in the early recognition of cardiovascular complications in tuberous sclerosis.
  • A systematic approach to screening and long-term follow-up is essential for managing cardiac rhabdomyomas and arrhythmias.
  • Enhanced knowledge empowers practitioners to improve the quality of life for affected children.

Keywords:
arrhythmiascardiac rhabdomyomasfollow-upscreeningtuberous sclerosis

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