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Epidemiology of Pediatric Cardiomyopathy in a Mediterranean Population

Alena Bagkaki1, Fragiskos Parthenakis1, Gregory Chlouverakis1

  • 1School of Medicine, University of Crete, 71 003 Heraklion, Greece.

Children (Basel, Switzerland)
|June 27, 2024
PubMed

Insights

Pediatric cardiomyopathy incidence in Crete is higher than previously reported for Caucasian populations. This study highlights the need for further research into Mediterranean pediatric cardiomyopathy prevalence and genetic factors.

Area of Science:

  • Pediatric Cardiology
  • Epidemiology
  • Genetics

Background:

  • Pediatric cardiomyopathy incidence is typically 1 per 100,000 children nationally.
  • Higher rates are noted in infants and specific populations.
  • Epidemiology in Mediterranean populations remains underdocumented.

Purpose of the Study:

  • To document the epidemiology of pediatric cardiomyopathy in a Mediterranean population.
  • To establish incidence and prevalence rates in Crete.
  • To identify common types and etiologies of pediatric cardiomyopathy.

Main Methods:

  • Retrospective study of children (<18 years) on Crete, Greece.
  • Data collected from 2002-2022 from tertiary pediatric cardiology services.
  • Analysis of incidence, prevalence, cardiomyopathy types, and identified etiologies.

Main Results:

  • Average annual incidence of 1.59 cases per 100,000 children.
  • Prevalence estimated at 26 cases per 100,000 children.
  • Dilated (50%) and hypertrophic (42.5%) cardiomyopathies were most common; etiology identified in 40%, with genetic diagnosis in 22.5%.

Conclusions:

  • Pediatric cardiomyopathy incidence in Crete exceeds rates reported for other Caucasian populations.
  • Further research is required for precise prevalence and genetic factors in Mediterranean populations.
  • Findings suggest unique epidemiological characteristics in this region.
Abstract

Keywords:
CreteMediterraneancardiomyopathychildhoodepidemiologypediatric cardiomyopathy

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