Related Experiment Video
Updated: Jun 22, 2025
Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
A Comparison between 2-Octyl Cyanoacrylate and Conventional Suturing for the Closure of Epiblepharon Incision Wounds
Chia-Chen Hsu1, Lung-Chi Lee1, Hsu-Chieh Chang2,3,4
1Department of Ophthalmology, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan.
Insights
Tissue adhesive (2-octyl cyanoacrylate) offers a safe and effective alternative to sutures for lower lid epiblepharon surgery in children. Caregivers reported high satisfaction with the adhesive
Area of Science:
- Ophthalmology
- Pediatric Surgery
- Wound Closure Techniques
Background:
- Tissue adhesives are established in ophthalmic surgery.
- Limited comparative data exists for 2-octyl cyanoacrylate versus sutures in pediatric lower lid epiblepharon repair.
- Asian children represent a specific demographic for this surgical condition.
Purpose of the Study:
- To compare the surgical efficacy of 2-octyl cyanoacrylate (SurgiSeal®) versus traditional sutures for lower lid epiblepharon repair in Asian children.
- To evaluate postoperative outcomes, including visual acuity, keratopathy, recurrence, complications, and aesthetics.
- To assess caregiver satisfaction with wound closure methods.
Main Methods:
- Retrospective case-control study of 20 pediatric patients undergoing epiblepharon surgery.
- Group A: Subcuticular suture plus 2-octyl cyanoacrylate. Group B: 6-O fast-absorbing surgical gut suture.
- Follow-up at 1, 4, and 12 weeks post-surgery.
Main Results:
- No significant differences in demographics, visual acuity, or surgical time between groups.
- Both methods improved visual acuity and reduced keratopathy severity.
- No recurrence or complications observed; similar aesthetic outcomes.
- Higher caregiver satisfaction with tissue adhesive due to ease of postoperative care.
Conclusions:
- 2-octyl cyanoacrylate (SurgiSeal®) is a simple, safe, and effective option for lower lid epiblepharon wound closure in children.
- Tissue adhesive provides comparable efficacy to conventional sutures with enhanced ease of postoperative care.
- This method is a viable alternative for pediatric ophthalmic surgery.
Abstract:
Background: Tissue adhesive has been widely used in ophthalmic surgery for various procedures, proving both effective and safe. However, no studies have compared the surgical efficacy of the tissue adhesive 2-octyl cyanoacrylate (SurgiSeal®) to that of traditional suture closure in Asian children undergoing surgery for lower lid epiblepharon. Methods: This is a single-center retrospective case-control study. Surgical correction for epiblepharon was performed on 22 patients from November 2019 to May 2023. A total of 20 patients who were followed up for at least 1 month were included for analysis. After standardized epiblepharon surgery, group A underwent wound closure with a subcuticular suture and 2-octyl cyanoacrylate, and group B underwent closure with a 6-O fast-absorbing surgical gut suture. Patients were followed up at 1, 4, and 12 weeks post-surgery. Results: A total of 10 patients (20 eyes) underwent skin closure with tissue adhesives (group A), and 10 patients (18 eyes) underwent wound closure using conventional suture material (group B). No significant differences in the sex ratio, mean age at operation, pre- and postoperative best-corrected visual acuity (BCVA), or average surgical time were observed between groups. Both groups exhibited improved postoperative BCVA, with symptom relief and a significant decrease in the severity of keratopathy after surgery. Neither recurrence nor complications were reported during follow-up. The aesthetic results were similar between groups, while caregivers of children in the tissue adhesive group expressed high satisfaction regarding the ease of postoperative care. Conclusions: Successful closure of lower lid epiblepharon surgery wounds in children can be performed using 2-octyl cyanoacrylate (SurgiSeal®). This method is simple, safe, and effective when compared to conventional sutures.
More Related Videos
00:20A Case Series of Successful Abdominal Closure Utilizing a Novel Technique Combining a Mechanical Closure System with a Biologic Xenograft that Accelerates Wound Healing
Published on: July 4, 2019
09:00Application of Straight-needle, Three-tailed, Knot-free, Peritoneal Sutures in Laparoscopic Transabdominal Preperitoneal Hernia Repair
Published on: November 12, 2021
