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Updated: Jun 22, 2025

Preparation and Characterization of Nanoliposomes for the Entrapment of Bioactive Hydrophilic Globular Proteins
Published on: August 31, 2019
Emerging Trends in Bilosomes as Therapeutic Drug Delivery Systems
Hemlata Kaurav1, Meenakshi Tripathi1, Simran Deep Kaur1
1School of Pharmaceutical Sciences, Shoolini University of Biotechnology and Management Sciences, P.O. Box 9, Solan 173229, Himachal Pradesh, India.
Bile acid-based nanocarriers, known as bilosomes, offer enhanced stability and mucosal penetration for improved drug delivery. Further research is needed to fully realize their pharmaceutical potential.
Area of Science:
- Pharmaceutical Sciences
- Nanotechnology
- Biochemistry
Background:
- Bile acids are amphiphilic compounds with unique molecular structures.
- New generation bilosomes exhibit enhanced stability in the gastrointestinal system.
- Bilosomes prevent drug degradation and improve mucosal penetration.
Purpose of the Study:
- To review the current scholarly attention on bilosomes as drug delivery carriers.
- To outline therapeutic areas where bilosomes have shown outstanding performance.
- To underscore the need for further investigation into bilosome applications.
Main Methods:
- Literature review of scholarly articles on bilosomes.
- Analysis of bilosome properties, including stability and penetration.
- Identification of therapeutic domains utilizing bilosomes for drug delivery.
Main Results:
- Bilosomes are emerging as a viable drug delivery modality.
- Enhanced stability and mucosal penetration are key advantages of bilosomes.
- Bilosomes show promise across several therapeutic domains.
Conclusions:
- Bilosomes represent a prospective nanocarrier for pharmaceutical administration.
- Further research and advancement are essential to fully understand bilosome potential.
- Bilosomes hold significant promise for diverse applications in drug delivery.
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