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Published on: January 7, 2018
Gut microbiota in insulin resistance: a bibliometric analysis
Weiwei Tian1, Li Liu1, Ruirui Wang2
1Key Lab.: Biological Evaluation of TCM Quality of the State Administration of Traditional Chinese Medicine, Translational Chinese Medicine Key Laboratory of Sichuan Province, Sichuan Engineering Technology Research Center of Genuine Regional Drug, Sichuan Provincial Engineering Research Center of Formation Principle and Quality Evaluation of Genuine Medicinal Materials, Sichuan Academy of Chinese Medical Sciences, Sichuan Institute for Translational Chinese Medicine, 610041 Chengdu, China.
This study analyzed 4,749 publications on gut microbiota and insulin resistance (IR). Key findings highlight inflammation, obesity, and the role of natural products like resveratrol as research hotspots in this field.
Area of Science:
- * Molecular Biology
- * Immunology
Background:
- * Insulin resistance (IR) is a primary driver of diabetes, linked to obesity, hypertension, and metabolic syndrome.
- * Growing evidence implicates the gut microbiota in the development of IR.
- * This bibliometric analysis maps the knowledge landscape of gut microbiota research in IR.
Purpose of the Study:
- * To summarize the knowledge structure of research on gut microbiota and insulin resistance.
- * To identify key trends, influential works, and research hotspots in this field.
Main Methods:
- * Bibliometric analysis of 4,749 publications (2013-2022) from Web of Science Core Collection.
- * Utilized tools including Microsoft Excel, Origin, R package (bibliometrix), Citespace, and VOSviewer for analysis and visualization.
- * Keywords and co-citation analysis were performed to identify prominent themes and researchers.
Main Results:
- * China and USA are leading contributors, with University of Copenhagen and Shanghai Jiao Tong University as top institutions.
- * "Gut microbiota," "insulin resistance," "obesity," and "inflammation" are the most frequent keywords.
- * Research hotspots include serum metabolome, natural products (resveratrol, flavonoids), and their connection to IR.
Conclusions:
- * This analysis provides a comprehensive overview of gut microbiota research in IR, covering hotspots, frontiers, pathogenesis, and treatment strategies.
- * Identifies key areas for future research in understanding and managing insulin resistance through gut microbiota modulation.
