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Doubling time in pulmonary and hepatic hydatid cysts

Yener Aydın1, Mesut Özgökçe2, Ali Bilal Ulas1

  • 1Department of Thoracic Surgery, Atatürk University Faculty of Medicine, Erzurum, Türkiye.

Turk Gogus Kalp Damar Cerrahisi Dergisi
|June 27, 2024
PubMed

Insights

Hydatid cysts grow faster in the lungs (approx. 10 weeks) than the liver (approx. 25 weeks). Cyst growth is also faster in children compared to adults, with lung cysts showing a significant difference between sexes.

Area of Science:

  • Parasitology
  • Medical Imaging
  • Clinical Medicine

Background:

  • Hydatid cysts, caused by Echinococcus granulosus, are a significant global health concern.
  • Understanding the growth dynamics of hydatid cysts is crucial for diagnosis and treatment planning.
  • Previous studies have not comprehensively evaluated factors influencing hydatid cyst doubling time.

Purpose of the Study:

  • To investigate variations in hydatid cyst doubling time based on patient age, sex, and cyst location (lung vs. liver).
  • To compare the growth rates of pulmonary and hepatic hydatid cysts.
  • To determine if age and sex influence the doubling time of hydatid cysts in different organs.

Main Methods:

  • Retrospective analysis of 138 hydatid cysts (55 pulmonary, 83 hepatic) between January 2012 and August 2023.
  • Data collection included patient demographics (age, sex) and cyst location.
  • Doubling time was calculated and compared across different patient groups and cyst locations.

Main Results:

  • Pulmonary hydatid cysts had a significantly shorter mean doubling time (73.4 days) than hepatic cysts (172.6 days).
  • Hydatid cysts in children demonstrated faster growth rates than in adults in both lung (p=0.119) and liver (p<0.001) locations.
  • A statistically significant difference in doubling time was observed between sexes for pulmonary cysts (p=0.018), but not for hepatic cysts (p=0.250).

Conclusions:

  • Hydatid cyst doubling time varies significantly by location, with faster growth in the lungs (approx. 10 weeks) compared to the liver (approx. 25 weeks).
  • Children exhibit accelerated hydatid cyst growth compared to adults in both pulmonary and hepatic locations.
  • Sex influences pulmonary hydatid cyst growth, suggesting potential sex-specific biological or environmental factors affecting parasite development.
Abstract

Keywords:
Doubling timehydatid cystliverlung.

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