Related Experiment Video
Updated: Jul 18, 2026

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
Published on: June 8, 2022
Systemic lupus erythematosus without clinical renal abnormalities: renal biopsy findings and clinical course
Abstract:
The extent and significance of renal biopsy abnormalities in patients with systemic lupus erythematosus (SLE) without clinical renal abnormalities is controversial. We report 11 consecutive SLE patients who were biopsied without clinical renal abnormalities. All 11 patients had mesangial changes either by light microscopy or by immunofluorescent staining, and none had changes of focal or diffuse proliferative glomerulonephritis. Additionally none had deterioration of renal function during the mean follow-up period of 6.3 years.
Related Concept Videos
Renal Corpuscle
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous capillaries...
Nephrotic Syndrome I : Introduction
Nephrotic Syndrome II : Assessment and Medical Management
Acute Kidney Injury I: Introduction
Acute Kidney Injury III: Clinical Manifestations
Chronic Kidney Disease II: Clinical Manifestations

