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Updated: Jun 22, 2025

Optogenetic Manipulation of Neural Circuits During Monitoring Sleep/wakefulness States in Mice
Published on: June 19, 2019
[The role of cerebral activation in the sleep-wake cycle]
E V Verbitsky1, Yu Yu Arapova2
1Southern Scientific Center of the Russian Academy of Sciences, Rostov-on-Don, Russia.
Abstract:
The development of views on cerebral activation in the wakefulness-sleep cycle, starting with the work of Constantin von Economo, is considered. The emphasis is on the cyclic activation of high-amplitude discharges in sleep, which, with known assumptions, can include K-complexes, as well as patterns of delta-like waves. Considering the participation of the peripheral nervous system in this, the integrative role of cyclic activation of high-amplitude discharges in the organization of the sleep-wake cycle is discussed.
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