Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Lichen planus pemphigoides: an immuno-electron microscopic study.

C Prost, F Tesserand, L Laroche

    The British Journal of Dermatology
    |July 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Updated S2 K guidelines for the management of bullous pemphigoid initiated by the European Academy of Dermatology and Venereology (EADV).

    Journal of the European Academy of Dermatology and Venereology : JEADV·2022
    Same author

    European Guidelines (S3) on diagnosis and management of mucous membrane pemphigoid, initiated by the European Academy of Dermatology and Venereology - Part II.

    Journal of the European Academy of Dermatology and Venereology : JEADV·2021
    Same author

    European guidelines (S3) on diagnosis and management of mucous membrane pemphigoid, initiated by the European Academy of Dermatology and Venereology - Part I.

    Journal of the European Academy of Dermatology and Venereology : JEADV·2021
    Same author

    A large epidemiological study of erythema multiforme in France, with emphasis on treatment choices.

    The British journal of dermatology·2018
    Same author

    InnOscent system: Advancing flavor analysis using an original gas chromatographic analytical device.

    Journal of chromatography. A·2018
    Same author

    [Criteria of the French bullous study group for day-care hospitalization billing for a patient with autoimmune bullous disease].

    Annales de dermatologie et de venereologie·2016

    Lichen planus pemphigoides differs from bullous pemphigoid in immune deposits. This study reveals distinct antigen localizations in lichen planus pemphigoides, aiding in differential diagnosis.

    Area of Science:

    • Immunodermatology
    • Autoimmune Blistering Diseases

    Background:

    • Lichen planus pemphigoides (LPP) is a rare autoimmune blistering disease.
    • Distinguishing LPP from bullous pemphigoid (BP) is crucial for accurate diagnosis and treatment.

    Observation:

    • Immuno-electron microscopy was used to localize G-immunoglobulin and C3 deposits in a case of LPP.
    • In the peribullous zone, deposits were found in the lamina lucida, similar to BP.
    • However, within the bulla itself, deposits were located along the floor, unlike the roof localization in BP.

    Findings:

    • The localization of immune deposits in LPP differs significantly from that in typical bullous pemphigoid.
    • This suggests that bullous pemphigoid antigen and lichen planus pemphigoides antigen have distinct tissue distributions.

    Related Experiment Videos

    Implications:

    • These findings may help differentiate LPP from BP based on immunoelectron microscopic analysis.
    • Understanding antigen localization is key to elucidating the pathogenesis of these related blistering diseases.