Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Seizures: Classification01:13

Seizures: Classification

331
Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
331
Arteries of the Lower Limbs01:24

Arteries of the Lower Limbs

186
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
186
Oppositional Defiant Disorder01:30

Oppositional Defiant Disorder

24
A persistent pattern of angry or irritable mood, defiant behavior, or vindictiveness characterizes Oppositional Defiant Disorder (ODD). Symptoms must occur over at least six months, involve interactions with individuals beyond siblings, and meet specific diagnostic criteria to be clinically significant. The disorder affects emotional regulation, social interactions, and behavior, often manifesting early in life and influencing long-term development and functioning.
Diagnostic Criteria and...
24

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Identifying Endocrinology Nurse Practitioners and Physician Associates Using Claims Data.

The journal for nurse practitioners : JNP·2026
Same author

Longitudinal Telesimulation Program and Rural Clinicians' Neonatal Resuscitation Performance.

Pediatrics·2026
Same author

Associations of rurality, child opportunity, and distance with use of pediatric asthma specialists.

The Journal of allergy and clinical immunology·2026
Same author

Artificial Urinary Sphincter-Sparing Vulvoplasty: A Case Report.

Cureus·2026
Same author

Budget Impact Analysis of the Balanced Opioid Initiative: A Cluster Randomized Trial Aimed at Deprescribing Opioids for Chronic Pain in Primary Care Settings.

Annals of family medicine·2026
Same author

Federal inspection timing, not compliance, associated with nursing home post-disaster outcomes.

Health affairs scholar·2026

Related Experiment Video

Updated: Jun 22, 2025

Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization
09:57

Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization

Published on: September 20, 2024

2.6K

Morbidity Associated with Deviation from Pediatric Status Epilepticus Guidelines.

Jillian Gregory1, Andrew Cohen2, Anya Cutler3

  • 1Tufts University School of Medicine, Boston, MA, United States; Department of Pediatrics, Division of Pediatric Critical Care, The Barbara Bush Children's Hospital at Maine Medical Center, Portland, ME, USA.

Epilepsy Research
|June 27, 2024
PubMed
Summary

High-dose benzodiazepine administration in pediatric status epilepticus (PSE) significantly increases intubation risk. Adhering to recommended doses in PSE management is crucial for better patient outcomes and reduced need for mechanical ventilation.

Keywords:
GuidelinesICUPediatricStatus epilepticus

More Related Videos

Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus
08:28

Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus

Published on: April 5, 2011

17.7K
Use of a Wireless Video-EEG System to Monitor Epileptiform Discharges Following Lateral Fluid-Percussion Induced Traumatic Brain Injury
09:16

Use of a Wireless Video-EEG System to Monitor Epileptiform Discharges Following Lateral Fluid-Percussion Induced Traumatic Brain Injury

Published on: June 21, 2019

25.6K

Related Experiment Videos

Last Updated: Jun 22, 2025

Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization
09:57

Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization

Published on: September 20, 2024

2.6K
Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus
08:28

Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus

Published on: April 5, 2011

17.7K
Use of a Wireless Video-EEG System to Monitor Epileptiform Discharges Following Lateral Fluid-Percussion Induced Traumatic Brain Injury
09:16

Use of a Wireless Video-EEG System to Monitor Epileptiform Discharges Following Lateral Fluid-Percussion Induced Traumatic Brain Injury

Published on: June 21, 2019

25.6K

Area of Science:

  • Pediatric Critical Care Medicine
  • Neurology
  • Emergency Medicine

Background:

  • Pediatric status epilepticus (PSE) management guidelines vary between institutions.
  • Standardized treatment protocols are essential for optimal patient care.
  • Benzodiazepine dosing is a critical factor in PSE management.

Purpose of the Study:

  • To analyze deviations from institutional PSE treatment guidelines.
  • To determine the impact of benzodiazepine dosage on intubation rates in PSE.
  • To evaluate the relationship between benzodiazepine administration and the need for mechanical ventilation.

Main Methods:

  • Retrospective cohort study of 66 pediatric intensive care unit (PICU) admissions for PSE (April 2019-April 2022).
  • Patients categorized by total benzodiazepine dose: low (≤0.05 mg/kg), recommended (0.05-0.2 mg/kg), and high (>0.2 mg/kg).
  • Intubation rates compared across dosage groups, controlling for hospital type and patient age.

Main Results:

  • 62% of patients received high-dose benzodiazepines (median 0.34 mg/kg).
  • The high-dose group was 15.9 times more likely to require intubation compared to recommended-dose groups.
  • Recommended-dose and low-dose groups had significantly lower intubation frequencies.

Conclusions:

  • Deviation towards high-dose benzodiazepine administration in PSE is common.
  • Higher benzodiazepine doses are strongly associated with increased intubation likelihood in pediatric patients.
  • Adherence to recommended benzodiazepine dosing protocols may reduce the need for intubation in PSE.