Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Antirheumatic medication during lactation.

C J Needs, P M Brooks

    British Journal of Rheumatology
    |August 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Lactating women can minimize infant exposure to nonsteroidal anti-inflammatory drugs (NSAIDs) by choosing medications with short half-lives and minimal milk transfer. Taking NSAIDs immediately after breastfeeding, with the next feeding after one half-life, further reduces infant exposure.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Australia needs an Ombudsman or Office for Research Integrity.

    Internal medicine journal·2016
    Same author

    The management of rheumatoid arthritis.

    The Australian journal of physiotherapy·2014
    Same author

    The patient is the teacher: ambulatory patient-centred student-based interprofessional education where the patient is the teacher who improves patient care outcomes.

    Internal medicine journal·2013
    Same author

    The clinical significance of indomethacin-probenecid interaction.

    British journal of clinical pharmacology·2012
    Same author

    The effect of frusemide on indomethacin plasma levels.

    British journal of clinical pharmacology·2012
    Same author

    Over the counter (OTC) oral remedies for arthritis and rheumatism: how effective are they?

    Inflammopharmacology·2008
    Same journal

    Sensorineural hearing loss, iritis and ankylosing spondylitis.

    British journal of rheumatology·1999
    Same journal

    Outcome in systemic vasculitis.

    British journal of rheumatology·1999
    Same journal

    Infection with an unenveloped DNA virus (TTV) associated with non-A to G hepatitis in patients with rheumatoid arthritis.

    British journal of rheumatology·1999
    Same journal

    Aortitis in relapsing polychondritis.

    British journal of rheumatology·1999
    Same journal

    Successful treatment with antithymocyte globulin and cyclosporin A of a severe aplastic anaemia associated with an eosinophilic fasciitis.

    British journal of rheumatology·1999
    Same journal

    Haemophagocytic syndrome in a patient with dermatomyositis.

    British journal of rheumatology·1999
    See all related articles

    Area of Science:

    • Pharmacology
    • Neonatal Medicine
    • Drug Safety

    Background:

    • Nonsteroidal anti-inflammatory drugs (NSAIDs) and antirheumatic drugs can transfer into human milk.
    • Infant exposure depends on drug properties and assay sensitivity.

    Purpose of the Study:

    • To identify NSAIDs suitable for breastfeeding mothers.
    • To provide guidelines for minimizing infant drug exposure.

    Main Methods:

    • Literature review of drug properties (half-life, milk transfer, metabolism).
    • Analysis of drug characteristics for minimal infant exposure.

    Main Results:

    • Ideal drugs have short half-lives, minimal milk presence, and inactive metabolites.
    • Short half-life propionic acid derivatives (e.g., ibuprofen, flurbiprofen) and diclofenac are suitable NSAIDs.

    Related Experiment Videos

  • Gold salts and corticosteroids appear safe; antimalarials require infant monitoring.

    • Conclusions:

    • Specific NSAIDs can be safely used by breastfeeding mothers.
    • Timing of NSAID administration relative to breastfeeding is crucial for infant safety.