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Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function

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Published on: January 26, 2024

An immersive virtual reality-based object-location memory task reveals spatial long-term memory alterations in

Tania Llana¹, Sara Garces-Arilla², M-Carmen Juan³

¹Neuroscience Institute of Principado de Asturias (INEUROPA), Faculty of Psychology, Plaza Feijoo s/n, Oviedo, Asturias 33003, Spain; Department of Psychology, University of Oviedo, Faculty of Psychology, Plaza Feijoo s/n, Oviedo, Asturias 33003, Spain.

Behavioural Brain Research

|June 27, 2024

Summary

Long-COVID patients exhibit significant object-location memory (OLM) deficits, particularly in delayed recall, compared to healthy controls. Immersive virtual reality (iVR) tasks effectively revealed these spatial memory impairments.

Keywords:

COVID Cognition Neuropsychology Span Spatial memory Virtual reality

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The Spatial Memory Game: Testing the Relationship Between Spatial Language, Object Knowledge, and Spatial Cognition

Published on: February 19, 2018

Area of Science:

Neuroscience
Cognitive Psychology
Infectious Disease Research

Background:

Long-COVID is associated with neurological and cognitive impairments, including memory dysfunction.
Medial temporal lobe dysfunction is observed in Long-COVID patients, impacting declarative memory.
Object-location memory (OLM) involves associating objects with their spatial positions.

Purpose of the Study:

To assess OLM deficits in Long-COVID patients using an immersive virtual reality (iVR) task.
To compare OLM performance between Long-COVID patients and healthy controls.
To explore correlations between OLM, general cognitive function (MoCA), and verbal/visuospatial span (VSTM/SSTM).

Main Methods:

An iVR-based OLM task was administered to 66 Long-COVID patients and 21 healthy controls.
Participants' performance metrics included correct responses, task attempts, and time investment.
Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA), verbal span (VSTM), and visuospatial span (SSTM).

Main Results:

Long-COVID patients demonstrated poorer OLM, making more attempts and taking longer than controls.
Delayed memory recall was more impaired than immediate recall in the Long-COVID group.
Higher MoCA scores correlated with faster immediate recall in Long-COVID patients; time since infection showed a slight association with recall accuracy.

Conclusions:

The iVR-based OLM task effectively identified spatial and long-term memory alterations in Long-COVID.
Findings confirm memory deficits in Long-COVID, highlighting the utility of iVR in neuropsychological research.
iVR spatial tasks offer a promising avenue for understanding and diagnosing cognitive impairments in post-viral syndromes.