A review of core outcome sets (COS) developed for different settings finds there is a subset of outcomes relevant for both research and routine care
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View abstract on PubMed
Summary
This summary is machine-generated.A small overlap exists between core outcome sets (COS) for research and routine care. This finding provides a foundation for aligning health research with real-world patient outcomes.
Area Of Science
- Health Services Research
- Clinical Trial Methodology
- Patient-Centered Outcomes
Background
- Core Outcome Sets (COS) are crucial for standardizing research and care evaluations.
- Comparing COS developed for research versus routine care settings is essential for bridging the research-practice gap.
Purpose Of The Study
- To compare outcomes included in COS for research with those in COS for routine care for the same health conditions.
- To identify common outcomes applicable to both research and clinical practice.
Main Methods
- Systematic review of existing COS for research and routine care.
- Categorization of outcomes using a standardized taxonomy.
- Analysis of outcome domain frequency and matched set comparisons based on health condition and scope.
Main Results
- A sample of 55 COS covered both research and routine care, while 246 were research-only and 76 were care-only.
- For health conditions, a median of 6 outcomes (range 3-15) were common to both research and care COS.
- COS developed without patient input were less likely to include life impact outcomes.
Conclusions
- A limited number of core outcomes are shared between research and routine care COS for a given condition.
- These shared outcomes offer a valuable starting point for integrating research findings into clinical practice and evaluation.
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