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Short-acting β2-agonists (SABA) overuse in asthma and patients' perceptions for this behavior
Claire D Visser1, Maaike R A Faay1, Ayşe Özdemir1
1Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, the Netherlands.
Respiratory Medicine
|June 27, 2024
Summary
Short-acting beta2-agonist (SABA) overuse persists in one-fifth of Dutch asthma patients, indicating a need for professional attention. Pharmacy dispensing data effectively identifies SABA overuse, guiding tailored interventions for better asthma control.
Area of Science:
- Respiratory Medicine
- Clinical Pharmacy
- Behavioral Science
Background:
- Short-acting beta2-agonist (SABA) overuse is linked to poor asthma control.
- The Global Initiative for Asthma (GINA) strategy has shifted recommendations for reliever therapy.
Purpose of the Study:
- Investigate SABA overuse and dispensing patterns in Dutch asthma patients.
- Validate pharmacy dispensing data for identifying SABA overuse.
- Understand patient perspectives on SABA use to inform interventions.
Main Methods:
- A 5-year (2017-2021) cross-sectional study using pharmacy dispensing data.
- Qualitative study with questionnaires and interviews for patients identified with SABA overuse.
- Analysis of behavioral drivers using theoretical frameworks.
Main Results:
- SABA overuse prevalence remained constant at 20.6% from 2017-2021.
- Pharmacy dispensing data showed 81% positive predictive value for SABA overuse.
- Seven themes identified patient capability, motivation, and opportunity as key behavioral drivers.
Conclusions:
- SABA overuse affects one-fifth of asthma patients in the Netherlands, necessitating healthcare professional attention.
- Dispensing data is a valid tool for identifying SABA overuse and selecting patients for intervention.
- Tailored behavioral interventions are crucial to address diverse patient needs and improve asthma management.
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