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Updated: Jun 22, 2025

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The HIV-1 Transcriptional Program: From Initiation to Elongation Control

Iván D'Orso1

  • 1Department of Microbiology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Journal of Molecular Biology
|June 27, 2024
PubMed
Summary

This review details the Human Immunodeficiency Virus type 1 (HIV-1) transcription control, focusing on how viral and cellular factors orchestrate gene expression. Understanding these mechanisms is crucial for developing new therapeutic strategies against HIV-1.

Keywords:
RNA polymerase II (Pol II)Viral latencyhuman immunodeficiency virus type-1 (HIV-1)transactivator of transcription (Tat)transcription

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