Visual Acuity Impairment from Inflammatory Isolated Sphenoid Sinus Disease

Area of Science:

• Ophthalmology
• Otorhinolaryngology
• Surgical Science

Background:

• Inflammatory isolated sphenoid sinus disease (ISSD) can lead to significant visual acuity (VA) deterioration.
• Endonasal endoscopic surgery (EES) is a primary treatment modality for ISSD.
• Understanding treatment outcomes and prognostic factors for VA recovery is crucial.

Purpose of the Study:

• To investigate treatment outcomes of EES for inflammatory ISSD causing VA loss.
• To identify determinants of prognosis for VA recovery in these patients.
• To assess the efficacy of EES in resolving associated symptoms.

Main Methods:

• Retrospective analysis of 13 patients (14 lesions) who underwent EES for inflammatory ISSD.
• Evaluation of VA using LogMAR scale, symptom resolution, and prognostic factors.
• Literature review on outcomes for ISSD-related VA impairments.

Main Results:

• Mycetoma was the most common etiology (n=5), followed by mucocele and sphenoiditis (n=4 each).
• An overall VA recovery rate of 87.5% was observed post-EES.
• Poor baseline VA and combined diplopia/ptosis were negative prognostic factors for VA recovery (p<0.05).

Conclusions:

• EES demonstrates a favorable prognosis for VA recovery in inflammatory ISSD.
• Treatment response varies by disease entity, with mucoceles showing better outcomes than sphenoiditis.
• Further research is warranted to personalize therapeutic strategies for improved outcomes.