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Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
Published on: March 24, 2023
[Conjecture on the next development direction of colorectal cancer and its minimally invasive surgery]
Z J Wang1, Z T Zhang2, Z L Ji3
1Department of General Surgery, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.
Abstract:
The surgical treatment of colorectal cancer will be more and more accurate and minimally invasive under the guidance of precision medicine. At the same time, it will derive and evolve non-surgical paths, such as immune checkpoint inhibitors and immune targeted therapy for microsatellite instability high/mismatch repair deficient colorectal cancer, and wait and watch path after neoadjuvant treatment for low advanced rectal cancer. Laparoscopic minimally invasive surgery for colorectal cancer will be gradually iterated by robots, which is the only way to intelligent surgery.
Insights
Precision medicine enhances colorectal cancer treatment accuracy and invasiveness. Future directions include non-surgical options and robotic surgery for intelligent cancer care.
Area of Science:
- Oncology
- Surgical Innovation
- Precision Medicine
Context:
- Colorectal cancer (CRC) treatment is evolving beyond traditional surgery.
- Advances in precision medicine are enabling more tailored therapeutic strategies.
- The field is exploring both non-surgical and advanced surgical approaches.
Purpose:
- To outline the future trajectory of colorectal cancer treatment.
- To highlight the integration of precision medicine in surgical and non-surgical CRC management.
- To discuss the evolution towards intelligent, robotic-assisted surgery.
Summary:
- Precision medicine is refining colorectal cancer surgery, making it more accurate and minimally invasive.
- Non-surgical pathways, including immunotherapy for specific CRC subtypes (microsatellite instability-high/mismatch repair-deficient), are expanding.
- A 'watch and wait' approach is emerging for select low-advanced rectal cancers post-neoadjuvant therapy.
- Laparoscopic surgery is transitioning to robotic systems, paving the way for intelligent surgical procedures.
Impact:
- Improved patient outcomes through personalized and less invasive treatments.
- Development of novel therapeutic strategies for challenging CRC subtypes.
- Increased efficiency and precision in colorectal cancer surgery via robotic integration.
- Establishment of 'intelligent surgery' as the future standard in CRC care.
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