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Oleogels: Versatile Novel Semi-Solid System for Pharmaceuticals
Vaishnavi U Pawar1, Akanksha D Dessai1, Usha Y Nayak2
1Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, 576104, Karnataka, India.
AAPS Pharmscitech
|June 27, 2024
Summary
Oleogels are versatile semi-solid systems offering stability and controlled release for food, cosmetics, and pharmaceuticals. Their formulation and characterization pave the way for innovative drug delivery systems.
Area of Science:
- Materials Science
- Pharmaceutical Sciences
- Food Science
Background:
- Oleogels are advanced semi-solid systems gaining traction in various industries.
- Their unique properties, including stability and controlled release, make them suitable for diverse applications.
- Understanding their composition and formulation is key to unlocking their full potential.
Purpose of the Study:
- To provide a comprehensive overview of oleogels, covering their composition, formulation, and characterization.
- To explore the diverse pharmaceutical and industrial applications of oleogels.
- To highlight the potential of oleogels in revolutionizing drug delivery systems.
Main Methods:
- Review of literature focusing on oleogel formulation strategies.
- Analysis of characterization techniques for oleogels, including rheology and microscopy.
- Exploration of oleogel applications in food, cosmetics, and pharmaceutical drug delivery.
Main Results:
- Oleogels can be effectively formulated using various oleogelators (waxes, fatty acids, ethyl cellulose, phytosterols) and edible oils.
- Characterization methods confirm their stability, texture, and rheological properties.
- Significant applications identified in topical, transdermal, and ocular drug delivery, alongside food and cosmetic uses.
Conclusions:
- Oleogels represent a promising platform for developing novel pharmaceutical formulations and drug delivery systems.
- Their versatility and tunable properties offer substantial potential for innovation across multiple sectors.
- Further research into oleogel technology can lead to enhanced product performance and therapeutic outcomes.
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