Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Electrolysis03:00

Electrolysis

26.3K
In a galvanic cell, the electrical work is done by a redox system on its surroundings as electrons produced by the spontaneous redox reactions are transferred through an external circuit. Alternatively, an external circuit does work on a redox system by imposing a voltage sufficient to drive an otherwise nonspontaneous reaction in a process known as electrolysis. For instance, recharging a battery involves the use of an external power source to drive the spontaneous (discharge) cell reaction in...
26.3K
Preparation and Reactions of Sulfides02:26

Preparation and Reactions of Sulfides

4.8K
Sulfides are the sulfur analog of ethers, just as thiols are the sulfur analog of alcohol. Like ethers, sulfides also consist of two hydrocarbon groups bonded to the central sulfur atom. Depending upon the type of groups present, sulfides can be symmetrical or asymmetrical. Symmetrical sulfides can be prepared via an SN2 reaction between 2 equivalents of an alkyl halide and one equivalent of sodium sulfide.
4.8K
Radical Substitution: Allylic Bromination01:27

Radical Substitution: Allylic Bromination

5.1K
In organic synthesis, the formation of products can be altered by changing the reaction conditions. For example, a dibromo addition product is formed when propene is treated with bromine at room temperature. In contrast, propene undergoes allylic substitution in non-polar solvents at high temperatures to give 3-bromopropene. In order to avoid the addition reaction, the bromine concentration must be kept as low as possible throughout the reaction. This can be achieved using N-bromosuccinimide...
5.1K
Oxidation-Reduction Reactions03:11

Oxidation-Reduction Reactions

64.7K
Oxidation–Reduction Reactions
64.7K
Preparation and Reactions of Thiols02:33

Preparation and Reactions of Thiols

6.1K
Thiols are prepared using the hydrosulfide anion as a nucleophile in a nucleophilic substitution reaction with alkyl halides. For instance, bromobutane reacts with sodium hydrosulfide to give butanethiol.
6.1K
Oxidation of Alkenes: Syn Dihydroxylation with Osmium Tetraoxide02:44

Oxidation of Alkenes: Syn Dihydroxylation with Osmium Tetraoxide

10.1K
Alkenes are converted to 1,2-diols or glycols through a process called dihydroxylation. It involves the addition of two hydroxyl groups across the double bond with two different stereochemical approaches, namely anti and syn. Dihydroxylation using osmium tetroxide progresses with syn stereochemistry.
10.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Probing the Role of Accessory Domains in Oxygen Stability of [FeFe]-Hydrogenases.

Journal of the American Chemical Society·2026
Same author

Structure Evolution in Hair Fibres During Strain and the Effect of Relative Humidity.

Applied spectroscopy·2026
Same author

Electrochemical Synthesis of Isolated Fluoride Reagents from PFAS.

Journal of the American Chemical Society·2026
Same author

Trypanocidal Activity of Dual Redox-Active Quinones: <i>Trypanosoma cruzi</i> Mitochondrion as a Target Organelle <i>In Vitro</i> and Anti-Inflammatory Properties <i>In Vivo</i>.

Pathogens (Basel, Switzerland)·2026
Same author

Highly <i>E</i>-Selective Alkene Isomerization Using Me<sub>4</sub>NF at Room Temperature.

The Journal of organic chemistry·2025
Same author

Oxidative benzylic C(sp<sup>3</sup>)-H functionalisation of electron-poor substrates with photoexcited DDQ.

Chemical science·2025

Related Experiment Video

Updated: Jun 22, 2025

Simple Methods for the Preparation of Non-noble Metal Bulk-electrodes for Electrocatalytic Applications
09:18

Simple Methods for the Preparation of Non-noble Metal Bulk-electrodes for Electrocatalytic Applications

Published on: June 21, 2017

11.4K

Bromide-Mediated Silane Oxidation: A Practical Counter-Electrode Process for Nonaqueous Deep Reductive

Mickaël E Avanthay1, Oliver H Goodrich2, David Tiemessen2

  • 1School of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, U.K.

JACS Au
|June 28, 2024
PubMed
Summary
This summary is machine-generated.

This study introduces a novel bromide-mediated silane oxidation counter-electrode for organic electrochemical reductions. This metal-free, scalable system enables deep reductions in undivided cells, enhancing sustainability.

More Related Videos

Simultaneous Multi-surface Anodizations and Stair-like Reverse Biases Detachment of Anodic Aluminum Oxides in Sulfuric and Oxalic Acid Electrolyte
10:27

Simultaneous Multi-surface Anodizations and Stair-like Reverse Biases Detachment of Anodic Aluminum Oxides in Sulfuric and Oxalic Acid Electrolyte

Published on: October 5, 2017

7.2K
A Method to Manipulate Surface Tension of a Liquid Metal via Surface Oxidation and Reduction
09:20

A Method to Manipulate Surface Tension of a Liquid Metal via Surface Oxidation and Reduction

Published on: January 26, 2016

15.3K

Related Experiment Videos

Last Updated: Jun 22, 2025

Simple Methods for the Preparation of Non-noble Metal Bulk-electrodes for Electrocatalytic Applications
09:18

Simple Methods for the Preparation of Non-noble Metal Bulk-electrodes for Electrocatalytic Applications

Published on: June 21, 2017

11.4K
Simultaneous Multi-surface Anodizations and Stair-like Reverse Biases Detachment of Anodic Aluminum Oxides in Sulfuric and Oxalic Acid Electrolyte
10:27

Simultaneous Multi-surface Anodizations and Stair-like Reverse Biases Detachment of Anodic Aluminum Oxides in Sulfuric and Oxalic Acid Electrolyte

Published on: October 5, 2017

7.2K
A Method to Manipulate Surface Tension of a Liquid Metal via Surface Oxidation and Reduction
09:20

A Method to Manipulate Surface Tension of a Liquid Metal via Surface Oxidation and Reduction

Published on: January 26, 2016

15.3K

Area of Science:

  • Organic electrochemistry
  • Electrochemical synthesis
  • Green chemistry

Background:

  • Counter-electrode processes are crucial for electrochemical reactions.
  • Existing methods for electrochemical reduction, especially deep reductions, are limited.
  • Sacrificial anodes and divided cells present sustainability and scalability challenges.

Purpose of the Study:

  • To develop a novel counter-electrode process for nonaqueous electrochemical reduction reactions.
  • To provide a sustainable and scalable alternative to sacrificial anodes and divided cells.
  • To enable deep reductions at very negative potentials in undivided cells.

Main Methods:

  • Development of a bromide-mediated silane oxidation counter-electrode.
  • Application in nonaqueous electrochemical reduction reactions within undivided cells.
  • Testing scalability and continuous flow implementation.

Main Results:

  • The developed system effectively functions as a counter-electrode for electrochemical reductions.
  • It is suitable for replacing sacrificial anodes or divided cells in various reactions.
  • The process is metal-free, uses inexpensive reagents, and is scalable.
  • Byproducts are reductively stable and easily removed.
  • Successful translation to a >100 g scale in continuous flow was demonstrated.

Conclusions:

  • A novel, efficient, and sustainable bromide-mediated silane oxidation counter-electrode has been developed.
  • This method offers a viable alternative for nonaqueous electrochemical reductions, particularly deep reductions.
  • The metal-free, scalable, and continuous flow compatible nature of this process advances green chemistry in electroorganic synthesis.