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Updated: Jun 22, 2025

Implantation of Total Artificial Heart in Congenital Heart Disease
07:27

Implantation of Total Artificial Heart in Congenital Heart Disease

Published on: July 18, 2014

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Born to Age: When Adult Congenital Heart Disease Converges With Geroscience

Philip Moons1,2,3, Ariane Marelli4

  • 1KU Leuven Department of Public Health and Primary Care, KU Leuven, Leuven, Belgium.

JACC. Advances
|June 28, 2024
PubMed

Insights

Congenital heart disease (CHD) patients are living longer, necessitating a deeper understanding of aging. This review explores demographic shifts, complications, and aging concepts to improve care for this growing population.

Area of Science:

  • Cardiology
  • Gerontology
  • Internal Medicine

Background:

  • Medical advancements have shifted the congenital heart disease (CHD) population towards older age groups.
  • Understanding the aging process is crucial for managing the evolving needs of CHD patients.
  • Systemic complications in younger CHD patients require consideration in the context of aging.

Purpose of the Study:

  • To analyze demographic changes in the CHD population.
  • To describe systemic complications in young CHD patients.
  • To explore aging concepts applicable to CHD and the role of inflammation.

Main Methods:

  • Review of demographic data in CHD.
  • Description of systemic complications in young CHD patients.
  • Discussion of general aging principles and inflammation's impact.

Main Results:

  • The CHD population is aging due to improved medical interventions.
  • Aging in CHD may present unique systemic complications.
  • Inflammation is a key factor potentially influencing aging in CHD.

Conclusions:

  • A comprehensive understanding of aging is essential for the future management of CHD.
  • Bridging knowledge between geroscientists and CHD experts is vital.
  • Further research into aging's impact on CHD function is warranted.

Keywords:
agingcongenital heart diseasefrailtygeroscienceheart defectinflammationoutcomes

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