Risk factors for infectious complications after gastrectomy in older patients
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View abstract on PubMed
Summary
This summary is machine-generated.Older gastric cancer patients face infectious complications after surgery. Male sex, low nutritional index, and high visceral fat are key preoperative risks, with longer operations increasing danger.
Area Of Science
- Oncology
- Geriatric Medicine
- Surgical Infections
Background
- Gastric cancer is a significant health concern in older adults.
- Postoperative infectious complications pose a major threat to patient recovery and outcomes.
- Identifying risk factors is crucial for improving surgical care in elderly gastric cancer patients.
Purpose Of The Study
- To identify preoperative and perioperative risk factors for infectious complications in older gastric cancer patients undergoing gastrectomy.
- To stratify risk based on the number of identified preoperative risk factors.
Main Methods
- Retrospective study of 504 gastric cancer patients aged over 65 who underwent radical gastrectomy.
- Receiver operating characteristic (ROC) curve analysis to determine cutoff values for perioperative factors.
- Logistic regression analysis to identify independent risk factors for infectious complications.
- Clavien-Dindo classification used to grade infectious complications.
Main Results
- 18.8% of patients developed infectious complications (grade II-V).
- Independent preoperative risk factors included male sex, low prognostic nutritional index (PNI), high visceral fat area, and total gastrectomy.
- Low PNI and long operative duration were identified as independent perioperative risk factors.
- Incidence of infectious complications increased significantly with the number of preoperative risk factors (from 6.7% with 0 factors to 47.6% with 4 factors).
Conclusions
- Older gastric cancer patients with multiple preoperative risk factors require careful consideration before gastrectomy.
- Minimizing operative time may help reduce the incidence of infectious complications in this vulnerable population.
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