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Updated: Jun 22, 2025

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation
Published on: July 16, 2014
Deep Brain Stimulation Mechanisms in Parkinson's Disease: Immediate and Long-Term Effects
Honglong Pei1, Zhenghan Wu1, Li Ma1
1Second Department of Neurosurgery, First Affiliated Hospital of Kunming Medical University, 650032 Kunming, Yunnan, China.
Abstract:
Deep brain stimulation (DBS) is a common therapy for managing Parkinson's disease (PD) in clinical practice. However, a complete understanding of its mode of action is still needed. DBS is believed to work primarily through electrical and neurochemical pathways. Furthermore, DBS has other mechanisms of action. This review explores the fundamental concepts and applications of DBS in treating PD, including its mechanisms, clinical implications, and recent research.
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