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Optimizing drug therapy for older adults: shifting away from problematic polypharmacy
Ruth Daunt1,2, Denis Curtin1,2, Denis O'Mahony1,2
1Department of Medicine (Geriatrics), School of Medicine, University College Cork, Cork, Ireland.
Expert Opinion on Pharmacotherapy
|June 28, 2024
Summary
Problematic polypharmacy is a growing public health threat, leading to adverse patient outcomes and increased healthcare costs. Addressing this requires an interdisciplinary approach, incorporating resources like artificial intelligence for effective interventions.
Area of Science:
- Pharmacology and Public Health
Background:
- Accelerated pharmaceutical development has led to increased polypharmacy.
- Problematic polypharmacy poses significant risks to patient health and healthcare systems.
Purpose of the Study:
- To review factors contributing to and consequences of problematic polypharmacy.
- To examine interventions and emerging solutions, including AI, for polypharmacy.
Main Methods:
- A comprehensive review of existing evidence on polypharmacy.
- Analysis of recent trials and innovative solutions.
Main Results:
- Polypharmacy is a growing threat with negative patient outcomes.
- Interdisciplinary strategies and AI show promise in addressing polypharmacy.
Conclusions:
- A multifaceted, interdisciplinary approach is essential to combat problematic polypharmacy.
- Leveraging all available resources, including artificial intelligence, is crucial for successful strategies.
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