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[Yeasts in leg ulcers].

J L Dereume

    Dermatologica
    |January 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Candida yeast infections were found in 24% of leg ulcers. Eliminating these yeasts with topical treatments did not consistently accelerate wound healing in patients.

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    Area of Science:

    • Medical Mycology
    • Dermatology
    • Infectious Diseases

    Background:

    • Leg ulcers are chronic wounds that can be susceptible to secondary infections.
    • Fungal infections, particularly by Candida species, can complicate wound healing.
    • Understanding the prevalence and impact of Candida in leg ulcers is crucial for effective management.

    Purpose of the Study:

    • To determine the prevalence of Candida species in leg ulcer infections.
    • To analyze potential risk factors associated with Candida colonization in leg ulcers.
    • To evaluate the effect of topical antifungal treatment on the healing rate of leg ulcers.

    Main Methods:

    • Cultures were performed on Sabouraud medium from leg ulcer lesions of 50 patients.
    • Statistical analysis was used to identify risk factors.

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  • Healing progression was monitored following topical treatment for yeast eradication.

    • Main Results:

    • Candida species were identified in 24% of the examined leg ulcer cultures.
    • Analysis of risk factors associated with Candida infection was conducted.
    • The complete disappearance of yeasts after topical treatment did not consistently correlate with accelerated wound healing.

    Conclusions:

    • Candida species represent a significant, albeit not universal, etiological agent in leg ulcer infections.
    • Topical antifungal therapy, while effective in eradicating yeast, may not be a primary driver for faster leg ulcer healing.
    • Further research is warranted to elucidate factors influencing healing in fungally colonized leg ulcers.