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Published on: June 11, 2019
Tip of the iceberg: extracardiac CT findings in infective endocarditis
M E Greer1, N Ghuman2, P T Johnson2
1School of Medicine, Georgetown University, Washington, DC, USA.
Insights
Infective endocarditis (IE) diagnosis can be challenging due to varied symptoms. This review details extracardiac complications found on CT scans, aiding early detection and management of this serious heart infection.
Area of Science:
- Radiology
- Cardiology
- Infectious Diseases
Background:
- Infective endocarditis (IE) presents with diverse symptoms, often mimicking other conditions, leading to diagnostic challenges.
- High-risk factors for IE include intravenous drug use, prior cardiac surgery, and indwelling cardiac devices.
- The modified Duke criteria are standard but have limitations in certain IE cases.
Purpose of the Study:
- To review common extracardiac complications of infective endocarditis (IE).
- To highlight characteristic computed tomography (CT) findings of IE complications across various body regions.
- To emphasize the role of emergency room radiologists in identifying unsuspected IE through CT.
Main Methods:
- Review of literature focusing on CT findings of IE extracardiac complications.
- Analysis of imaging features in the chest, abdomen, pelvis, and brain associated with IE.
- Discussion of diagnostic challenges and the utility of CT in early IE detection.
Main Results:
- Common extracardiac complications of IE visualized on CT include embolic events, abscesses, and mycotic aneurysms.
- CT can reveal secondary signs of IE in the chest, abdomen, pelvis, and brain, even when IE is not initially suspected.
- Radiologists can facilitate prompt IE management by recognizing these CT findings.
Conclusions:
- CT plays a crucial role in identifying extracardiac manifestations of infective endocarditis (IE).
- Early recognition of IE complications on CT by emergency room radiologists can expedite diagnosis and treatment.
- Echocardiography remains essential for confirming IE when suspected based on CT findings.
Abstract:
Infective endocarditis (IE) is a disease with high morbidity and mortality rate, but diagnosis is confounded by diverse clinical presentations, which mimic other pathologies. A history of illicit intravenous drug use, previous cardiac valve surgery, and indwelling intracardiac devices increases the risk for developing infective endocarditis. The modified Duke criteria serve as the standard diagnostic tool, though its accuracy is reduced in certain cases. Radiologists in the Emergency Room setting reading body CT may be the first to identify the secondary extra-cardiac complications and facilitate expeditious management by considering otherwise unsuspected infective endocarditis. This review highlights common extracardiac complications of IE and their corresponding CT findings in the chest, abdomen, pelvis, and brain. If IE is suspected radiologists should suggest further investigation with echocardiography.
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