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Updated: Jun 22, 2025

Induction of Cerebral Arterial Gas Embolism in Rat
Published on: October 18, 2024
[Cerebral gas embolism as a complication of diffuse interstitial lung disease]
Juan Ramon Y Cajal Calvo1, Laura Perez Abad2, Victoria Mayoral Campos3
1Servicio de Radiodiagnóstico. Hospital Clínico Lozano Blesa. Zaragoza. España . jramonycajalc@gmail.com.
Introduction:
Cerebral gas embolism is an unusual but extremely serious condition that occurs when air is introduced into the arterial or venous circulation of the brain. Although rare, it can lead to significant neurological deficits and even the death of the patient.
Clinical Case:
76-year-old patient with pre-existing diffuse interstitial lung disease, who experienced a massive stroke due to spontaneous pneumomediastinum. Her presentation included confusion, seizures, and motor weakness. Imaging tests revealed air bubbles in the cerebral sulci and hypodense areas in the cerebellum and parietooccipitals. In addition, pneumothorax and air in the upper mediastinum were noted on chest radiographs and chest CT scan. Despite therapeutic measures such as hyperbaric oxygen, the patient unfortunately died due to multiple organ failure.
Discussion:
The diagnosis of cerebral gas embolism generally involves performing a cerebral computed tomography, which is highly sensitive for detecting the presence of air in the cerebral vessels. Management includes monitoring of vital and neurological signs, as well as specific measures such as airway closure, venous catheter aspiration, Trendelenburg positioning, and hyperbaric oxygen.
Conclusion:
Cerebral gas embolism is a potentially fatal condition that requires a brain computed tomography for diagnosis and it is vitally important to know the prevention measures to avoid the appearance of this complication and also to know the general measures to adopt when it occurs.
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