Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hepatitis E virus replication is maintained in proliferative cells within the intestinal crypt.

Science advances·2026
Same author

A deep learning-based computational pipeline predicts developmental outcome in retinal organoids.

PLoS biology·2026
Same author

Establishing an auxin-inducible GFP nanobody-based acute protein knockdown system to mimic hypomorphic mutations during early medaka embryogenesis.

Biology open·2025
Same author

Discovery and characterisation of gene by environment and epistatic genetic effects in a vertebrate model.

bioRxiv : the preprint server for biology·2025
Same author

Natural genetic variation quantitatively regulates heart rate and dimension.

Nature communications·2025
Same author

Telomerase RNA structural heterogeneity in living human cells detected by DMS-MaPseq.

Nature communications·2025

Related Experiment Video

Updated: Jun 22, 2025

Author Spotlight: An Accurate and Quantitative Approach to Study Visual Feature Selectivity of the Optokinetic Reflex in Mice
09:28

Author Spotlight: An Accurate and Quantitative Approach to Study Visual Feature Selectivity of the Optokinetic Reflex in Mice

Published on: June 23, 2023

2.5K

Characterizing medaka visual features using a high-throughput optomotor response assay.

Risa Suzuki1,2, Jia Zheng Woo1, Thomas Thumberger1

  • 1Centre for Organismal Studies (COS), Heidelberg University, Heidelberg, Germany.

Plos One
|June 28, 2024
PubMed
Summary
This summary is machine-generated.

Medaka fish (Oryzias latipes) larvae exhibit robust optomotor responses (OMR) to moving stripes, revealing strain-specific differences and a training effect. This assay enables genetic studies of visual functions in vertebrates.

More Related Videos

Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats
07:08

Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats

Published on: January 10, 2019

10.0K
The Optokinetic Response as a Quantitative Measure of Visual Acuity in Zebrafish
04:56

The Optokinetic Response as a Quantitative Measure of Visual Acuity in Zebrafish

Published on: October 9, 2013

20.5K

Related Experiment Videos

Last Updated: Jun 22, 2025

Author Spotlight: An Accurate and Quantitative Approach to Study Visual Feature Selectivity of the Optokinetic Reflex in Mice
09:28

Author Spotlight: An Accurate and Quantitative Approach to Study Visual Feature Selectivity of the Optokinetic Reflex in Mice

Published on: June 23, 2023

2.5K
Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats
07:08

Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats

Published on: January 10, 2019

10.0K
The Optokinetic Response as a Quantitative Measure of Visual Acuity in Zebrafish
04:56

The Optokinetic Response as a Quantitative Measure of Visual Acuity in Zebrafish

Published on: October 9, 2013

20.5K

Area of Science:

  • Neuroscience
  • Genetics
  • Developmental Biology

Background:

  • Medaka fish (Oryzias latipes) are a valuable model organism for studying vertebrate visual system genetics.
  • Understanding visual functions like acuity and sensitivity is crucial for developmental and functional trait research.

Purpose of the Study:

  • To establish a high-throughput optomotor response (OMR) assay for medaka larvae.
  • To investigate visual functions including visual acuity and contrast sensitivity using this assay.
  • To provide an open-source tool for quantitative phenotype mapping of visual traits.

Main Methods:

  • Utilized medaka larvae in a linear arena with a tablet display for adjustable moving stripes (speed, width, color, contrast).
  • Employed the Fish Stripes software for precise control over visual stimuli.
  • Recorded optomotor responses induced by black and white stripes presented from below.

Main Results:

  • Demonstrated robust optomotor responses in medaka larvae to moving black and white stripes.
  • Detected significant strain-specific differences in OMR among established medaka inbred strains.
  • Observed a training effect where initial exposure to thick stripes improved responses to narrower stripes.

Conclusions:

  • The developed OMR assay is an efficient tool for quantitative phenotype mapping of visual functions.
  • The assay facilitates research into visual acuity, trainability, color sensitivity, and retinal regeneration.
  • This open-source setup is a prerequisite for addressing the genetic basis of visual processes in medaka.