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Targeted Cancer Therapies

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...

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Cancer Therapies

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
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Related Experiment Video

Updated: Jun 22, 2025

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System

Published on: December 11, 2016

Drug repurposing for cancer.

Juni Banerjee¹, Anand Krishna Tiwari¹, Shuvomoy Banerjee¹

¹Department of Biotechnology and Bioengineering, Institute of Advanced Research (IAR), Gandhinagar, Gujarat, India.

Progress in Molecular Biology and Translational Science

|June 28, 2024

Summary

Drug repurposing offers a novel strategy to advance cancer therapeutics by utilizing approved drugs. This approach, enhanced by new technologies and combination therapies, aims to improve treatment efficacy against complex malignancies.

Keywords:

Cancer therapy Chemotherapeutics Drug delivery Drug designing Drug repurposing

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Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts

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Published on: July 25, 2020

Area of Science:

Oncology
Pharmacology
Biotechnology

Background:

Cancer therapeutics face challenges due to complex tumor biology and evolving treatment resistance.
Drug repurposing presents a strategic paradigm shift in developing new cancer treatments.

Purpose of the Study:

To comprehend the strategic deployment and historical evolution of drug repurposing in oncology.
To explore advanced methodologies for accelerating drug repurposing in cancer therapy.
To assess breakthroughs and combination therapies involving repurposed drugs for enhanced efficacy.

Main Methods:

Review of historical drug repurposing strategies.
Exploration of modern tools: high-throughput screening, omics technologies, and artificial intelligence (AI).
Analysis of combination therapies involving repurposed drugs.

Main Results:

Identification of breakthroughs expanding the repertoire of repurposed drug candidates in cancer.
Assessment of major categories of repurposed drugs.
Elucidation of combination therapies targeting heterogeneous cancer populations and overcoming resistance.

Conclusions:

Drug repurposing, supported by advanced technologies and combinatorial approaches, holds significant potential to advance cancer therapeutics.
This strategy offers a path towards personalized and synergistic treatments, addressing key challenges in oncology.