Association between metabolic score of visceral fat and carotid atherosclerosis in Chinese health screening population: a cross-sectional study
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View abstract on PubMed
Summary
This summary is machine-generated.The metabolic score for visceral fat (METS-VF) is linked to carotid atherosclerosis (CAS) in a nonlinear manner. The risk of CAS increases with METS-VF until a certain point, after which the association plateaus.
Area Of Science
- Cardiovascular Health
- Metabolic Syndrome
- Medical Diagnostics
Background
- The metabolic score for visceral fat (METS-VF) measures visceral and intra-abdominal fat accumulation.
- The association between METS-VF and carotid atherosclerosis (CAS) requires further investigation.
Purpose Of The Study
- To examine the relationship between METS-VF and CAS in Chinese adults.
- To identify potential nonlinear associations and inflection points in this relationship.
Main Methods
- A cross-sectional study of 7089 Chinese adults was conducted.
- Multivariable logistic regression and generalized additive models (GAM) were used.
- Segmented logistic regression identified inflection points in the METS-VF and CAS association.
Main Results
- A positive correlation was found between METS-VF and CAS (OR: 1.824).
- GAM analysis revealed a nonlinear association with an inflection point at METS-VF = 8.09.
- CAS risk significantly increased with METS-VF below 8.09, but not at or above this level.
Conclusions
- METS-VF and CAS exhibit a positive nonlinear correlation.
- A saturation effect was observed at a METS-VF of 8.09, indicating a threshold for increased CAS risk.
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